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KMID : 0377520030280020107
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Chung-Ang Journal of Medicine
2003 Volume.28 No. 2 p.107 ~ p.119
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Principle of Antibiotic Usage in Treatment of Community-Acquired Pneumonia in Immunocompetent Adults
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Shin Jong-Wook
Kim Jae-Yeol
Park In-Won
Choi Byoung-Whui
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Abstract
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Community-Acquired Pneumonia (CAP) is still one of the leading causes of major morbidity and mortality of infectious diseases in immunocompetent hosts. Although antibiotics are mainstay of treatment for CAP, a definite guideline remains to be uncertain. This uncertainty currently forces physician out to make therapeutic challenge with modest danger. So we intend to prepare a guideline for antibiotic usage for CAP. Most causative etiologies contain Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, Chlamydia pneurnoniae, Legionella pneumophila. Antibiotics should be administered to cover all these organisms when a definitive etiologic microorganism are not determined. Except for aspiration pneumonia, one pneumonia usually has one causative agent. Drug-resistant Streptococcus pneumoniae and Haemophilus influenzae should be considered for antibiotic choice. Severity of CAP depends on cardiopulmonary physiologic status, age and comorbid conditions. In this regard, fluoroquinolones and β -lactam antibiotics and macrolides can be successfully administered for the treatment of CAP.
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KEYWORD
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Community-Acquired pneumonia, Fluoroquinoles, β-lactam, Macrolides
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